Publications

Recent Publications from Members of the Department

Integrated analysis of the tumor microenvironment using a reconfigurable microfluidic cell culture platform.
Sethakorn N, Heninger E, Breneman MT, Recchia E, Ding AB, Jarrard DF, Hematti P, Beebe DJ, Kosoff D.
FASEB J. 2022 Oct;36(10):e22540. doi: 10.1096/fj.202200684RR.
PMID: 36083096

Mechanisms of the intestinal and urinary microbiome in kidney stone disease.
Miller AW, Penniston KL, Fitzpatrick K, Agudelo J, Tasian G, Lange D.
Nat Rev Urol. 2022 Sep 20. doi: 10.1038/s41585-022-00647-5. Online ahead of print.
PMID: 36127409

Perceptions and Experiences of Gender Equity amongst Endourologists.
Martin LH, Best SL, Semins MJ, Haslam R, Agnor R, Seideman C.
J Endourol. 2022 Sep 16. doi: 10.1089/end.2022.0236. Online ahead of print.
PMID: 36112672

Reversible epigenetic alterations regulate class I HLA loss in prostate cancer.
Rodems TS, Heninger E, Stahlfeld CN, Gilsdorf CS, Carlson KN, Kircher MR, Singh A, Krueger TEG, Beebe DJ, Jarrard DF, McNeel DG, Haffner MC, Lang JM.
Commun Biol. 2022 Sep 1;5(1):897. doi: 10.1038/s42003-022-03843-6.
PMID: 36050516

Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma.
Islam SS, Qassem K, Islam S, Parag RR, Rahman MZ, Farhat WA, Yeger H, Aboussekhra A, Karakas B, Noman ASM.
Cell Death Dis. 2022 Aug 9;13(8):696. doi: 10.1038/s41419-022-05126-8.
PMID: 35945195

Recurrent UPJ obstruction following paediatric pyeloplasty is associated with an initial <2.5cm incision open surgical approach.
Zu’bi F, O’Kelly F, Farhat WA, Chua M, Shiff M, Gao B, Kim JK, Kutbi RA, Pokarowski M, Koyle MA.
Urology. 2022 Aug 21:S0090-4295(22)00721-X. doi: 10.1016/j.urology.2022.08.017. Online ahead of print.

Prostate cancer cells demonstrate unique metabolism and substrate adaptability acutely after androgen deprivation therapy.
Filon MJ, Gillette AA, Yang B, Khemees TA, Skala MC, Jarrard DF.
Prostate. 2022 Aug 18. doi: 10.1002/pros.24428. Online ahead of print.
PMID: 35980831

Increased COX-1 expression in benign prostate epithelial cells is triggered by mitochondrial dysfunction.
Hudson CN, He K, Pascal LE, Liu T, Myklebust LK, Dhir R, Srivastava P, Yoshimura N, Wang Z, Ricke WA, DeFranco DB.
Am J Clin Exp Urol. 2022 Aug 15;10(4):234-245. eCollection 2022.
PMID: 36051613

Differentiation of benign from malignant solid renal lesions with MRI-based radiomics and machine learning.
Massa’a RN, Stoeckl EM, Lubner MG, Smith D, Mao L, Shapiro DD, Abel EJ, Wentland AL.
Abdom Radiol (NY). 2022 Aug;47(8):2896-2904. doi: 10.1007/s00261-022-03577-3. Epub 2022 Jun 20.
PMID: 35723716

Association of Analgesic Block With the Incidence of Complications Following Hypospadias Surgery; A Meta-Analysis.
Adler AC, Bhatia VP, Chandrakantan A, Nathanson BH, Ouellette L, Austin PF.
Urology. 2022 Aug;166:11-17. doi: 10.1016/j.urology.2022.03.002. Epub 2022 Mar 12.
PMID: 35292293 Review.

Islet allografts expressing a PD-L1 and IDO fusion protein evade immune rejection and reverse preexisting diabetes in immunocompetent mice without systemic immunosuppression.
Paul PK, Das R, Drow T, Nylen EA, de Souza AH, Wang Z, Wood MW, Belt Davis D, Bjorling DE, Galipeau J.
Am J Transplant. 2022 Jul 27. doi: 10.1111/ajt.17162. Online ahead of print.
PMID: 35897156

Robotic partial nephrectomy in the pediatric population: Cumulative experience at a large pediatric hospital.
Antar A, Bachtel HA, Bates JN, Kim SJ, Saleem A, Bhatia V, Link RE, Koh CJ.
J Pediatr Urol. 2022 Jul 2:S1477-5131(22)00299-6. doi: 10.1016/j.jpurol.2022.06.029. Online ahead of print.
PMID: 35931605

Obesity and “obesity-related” cancers: are there body mass index cut-points?
Murtha JA, Liu N, Birstler J, Hanlon BM, Venkatesh M, Hanrahan LP, Borza T, Kushner DM, Funk LM.
Int J Obes (Lond). 2022 Jul 11. doi: 10.1038/s41366-022-01178-0. Online ahead of print.
PMID: 35817851

A Prospective Analysis of Opioid Use Following Outpatient Pediatric Urologic Surgery.
Sherrer R, Su R, O’Kelly F, Borza T, Byrne A, Finup J, Farhat W.
Urology. 2022 Jul 16:S0090-4295(22)00597-0. doi: 10.1016/j.urology.2022.07.006. Online ahead of print.
PMID: 35853508

Complementary proteome and glycoproteome access revealed through comparative analysis of reversed phase and porous graphitic carbon chromatography.
Delafield DG, Miles HN, Liu Y, Ricke WA, Li L.
Anal Bioanal Chem. 2022 Jul;414(18):5461-5472. doi: 10.1007/s00216-022-03934-7. Epub 2022 Feb 9.
PMID: 35137243

Imaging in stone diagnosis and surgical planning.
Serrell EC, Best SL.
Curr Opin Urol. 2022 Jul 1;32(4):397-404. doi: 10.1097/MOU.0000000000001002.
PMID: 35749786 Review.

Primary Contributors to Dietary Acid Load in Patients with Urolithiasis.
Betz MV, Penniston KL.
J Ren Nutr. 2022 Jun 22:S1051-2276(22)00107-8. doi: 10.1053/j.jrn.2022.05.005. Online ahead of print.
PMID: 35752401

The duration of stone disease and the impact of a stone event on patients’ quality of life.
Raizenne B, Deyirmendjian C, Bechis SK, Sur RL, Nakada SY, Antonelli JA, Streeper N, Sivalingam S, Viprakasit D, Averch TD, Landman J, Chi T, Pais VM Jr, Chew BH, Bird V, Andonian S, Canvasser NE, Harper JD, Penniston KL, Bhojani N.
J Endourol. 2022 Jun 18. doi: 10.1089/end.2021.0897. Online ahead of print.
PMID: 35722905

Differentiation of benign from malignant solid renal lesions with MRI-based radiomics and machine learning.
Massa’a RN, Stoeckl EM, Lubner MG, Smith D, Mao L, Shapiro DD, Abel EJ, Wentland AL.
Abdom Radiol (NY). 2022 Jun 20. doi: 10.1007/s00261-022-03577-3. Online ahead of print.
PMID: 35723716

Quality of Life of Urolithiasis Patients During the COVID-19 Pandemic: A Multi-Institutional Cross-Sectional Study.
Wong VKF, Bhojani N, Bird V, Streeper N, Nakada SY, Penniston K, Chew BH.
J Endourol. 2022 Jun;36(6):798-806. doi: 10.1089/end.2021.0298. Epub 2022 May 17.
PMID: 34569279

Acute Management of Prolonged, Recalcitrant Priapism in a Pediatric Patient.
Sherrer R, Otto M, Srinivasan S, Grinde K, Farhat WA.
Pediatrics. 2022 Jun 1;149(6):e2021054941. doi: 10.1542/peds.2021-054941.
PMID: 35543028

External validation of a low fidelity dry-lab platform to enhance loupes surgical skills techniques for hypospadias repair.
Bhatia VP, Wolf J, Farhat WA, Lewis B, Gralnek DR, Eliceiri KW, O’Kelly F.
J Pediatr Urol. 2022 May 7:S1477-5131(22)00167-X. doi: 10.1016/j.jpurol.2022.04.020. Online ahead of print.
PMID: 35644791

Screening and management of bladder and bowel dysfunction in general pediatric outpatient clinic: a prospective observational study.
Sumboonnanonda A, Sawangsuk P, Sungkabuth P, Muangsampao J, Farhat WA, Piyaphanee N.
BMC Pediatr. 2022 May 17;22(1):288. doi: 10.1186/s12887-022-03360-9.
PMID: 35581653

Longitudinal Molecular Profiling of Circulating Tumor Cells in Metastatic Renal Cell Carcinoma.
Bootsma M, McKay RR, Emamekhoo H, Bade RM, Schehr JL, Mannino MC, Singh A, Wolfe SK, Schultz ZD, Sperger J, Xie W, Signoretti S, Kyriakopoulos CE, Kosoff D, Abel EJ, Helzer KT, Rydzewski N, Bakhtiar H, Shi Y, Blitzer G, Bassetti M, Floberg J, Yu M, Sethakorn N, Sharifi M, Harari PM, Choueiri TK, Lang JM, Zhao SG.
J Clin Oncol. 2022 May 26:JCO2200219. doi: 10.1200/JCO.22.00219. Online ahead of print.
PMID: 35617646

Association between baseline body mass index and survival in men with metastatic hormone-sensitive prostate cancer: ECOG-ACRIN CHAARTED E3805.
Morgans AK, Chen YH, Jarrard DF, Carducci M, Liu G, Eisenberger M, Plimack ER, Bryce A, Garcia JA, Dreicer R, Vogelzang NJ, Picus J, Shevrin D, Hussain M, DiPaola RS, Cella D, Sweeney CJ; ECOG-ACRIN E3805 Investigators.
Prostate. 2022 May 10. doi: 10.1002/pros.24369. Online ahead of print.
PMID: 35538398

Fresh tissue procurement and preparation for multicompartment and multimodal analysis of the prostate tumor microenvironment.
Vitek RA, Huang W, Geiger PG, Heninger E, Lang JM, Jarrard DF, Beebe DJ, Johnson BP.
Prostate. 2022 May;82(7):836-849. doi: 10.1002/pros.24326. Epub 2022 Feb 28.
PMID: 35226381

Editorial Comment: “Should Ureteral Access Sheaths Be Used Routinely for Ureteroscopy?”.
Best SL.
J Endourol. 2022 May;36(5):588. doi: 10.1089/end.2021.0940.
PMID: 35018805

Impact of native nephrectomy on hypertension outcomes in pediatric kidney transplant recipients: a 10-year institutional experience.
Kim JK, Lorenzo AJ, Raveendran L, Chua ME, Ming JM, Farhat WA, Koyle MA.
Pediatr Surg Int. 2022 Apr;38(4):623-629. doi: 10.1007/s00383-022-05080-8. Epub 2022 Feb 13.
PMID: 35152307

Botulinum Toxin Injection of the External Sphincter in Adults with Cerebral Palsy.
Su R, Bushman W.
J Urol. 2022 Apr 21:101097JU0000000000002710. doi: 10.1097/JU.0000000000002710. Online ahead of print.
PMID: 35446146 No abstract available.

Randomized trial of prophylactic antibiotics vs. placebo after midshaft-to-distal hypospadias repair: the PROPHY Study.
Faasse MA, Farhat WA, Rosoklija I, Shannon R, Odeh RI, Yoshiba GM, Zu’bi F, Balmert LC, Liu DB, Alyami FA, Beaumont JL, Erickson DL, Gong EM, Johnson EK, Judd S, Kaplan WE, Kaushal G, Koyle MA, Lindgren BW, Maizels M, Marcus CR, McCarter KL, Meyer T, Qureshi T, Saunders M, Thompson T, Yerkes EB, Cheng EY.
J Pediatr Urol. 2022 Apr;18(2):171-177. doi: 10.1016/j.jpurol.2022.01.008. Epub 2022 Jan 25.
PMID: 35144885 Clinical Trial.

Models of Renal Cell Carcinoma Used to Investigate Molecular Mechanisms and Develop New Therapeutics.
Shapiro DD, Virumbrales-Muñoz M, Beebe DJ, Abel EJ.
Front Oncol. 2022 Apr 7;12:871252. doi: 10.3389/fonc.2022.871252. eCollection 2022.
PMID: 35463327

Ultrasound Assessment of Penile Blood Flow Following Caudal Block in Children; A Pilot Study.
Adler AC, Bhatia VP, Chandrakantan A, Austin PF.
Urology. 2022 Apr 13:S0090-4295(22)00285-0. doi: 10.1016/j.urology.2022.03.029. Online ahead of print.
PMID: 35429493

Microphysiological model of renal cell carcinoma to inform anti-angiogenic therapy.
Virumbrales-Muñoz M, Ayuso JM, Loken JR, Denecke KM, Rehman S, Skala MC, Abel EJ, Beebe DJ.
Biomaterials. 2022 Apr;283:121454. doi: 10.1016/j.biomaterials.2022.121454. Epub 2022 Mar 11.
PMID: 35299086

Decline in Respiratory Functions in Hospitalized SARS-CoV-2 Infected Cancer Patients Following Cytotoxic Chemotherapy-An Additional Risk for Post-chemotherapy Complications.Al-Mozaini MA, Islam M, Noman ASM, Karim AR, Farhat WA, Yeger H, Islam SS.
Front Med (Lausanne). 2022 Mar 10;9:835098. doi: 10.3389/fmed.2022.835098. eCollection 2022.
PMID: 35360723

Redefining the Spectrum of Pentosan Polysulfate Retinopathy: Multimodal Imaging Findings from a Cross-Sectional Screening Study.
Dieu AC, Whittier SA, Domalpally A, Pak JW, Voland RP, Boyd KM, Gottlieb JL, Crabtree GS, Giles DL, McAchran SE, Mititelu M.
Ophthalmol Retina. 2022 Mar 24:S2468-6530(22)00131-2. doi: 10.1016/j.oret.2022.03.016. Online ahead of print.
PMID: 35339727

E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice.
Pascal LE, Igarashi T, Mizoguchi S, Chen W, Rigatti LH, Madigan CG, Dhir R, Bushman W, DeFranco DB, Yoshimura N, Wang Z.
Aging (Albany NY). 2022 Mar 31;14(7):2945-2965. doi: 10.18632/aging.203994. Epub 2022 Mar 31.
PMID: 35361739 Free PMC article.

Hospitalization following pediatric kidney transplantation: An international comparison among a Canadian pediatric transplant center, North American Pediatric Renal Trials and Collaborative Studies, and Cooperative European Pediatric Renal Transplant Initiative registry data.
Kim JK, Lorenzo AJ, Tönshoff B, Chua ME, Raveendran L, Krupka K, Teoh CW, Ming JM, Topaloglu R, Dello Strologo L, Farhat WA, Koyle MA.
Pediatr Transplant. 2022 Mar 27:e14273. doi: 10.1111/petr.14273. Online ahead of print.
PMID: 35340109

Contrast-enhanced CT immediately following percutaneous microwave ablation of cT1a renal cell carcinoma: Optimizing cancer outcomes.
Koebe SD, Curci NE, Caoili EM, Triche BL, Dreyfuss LD, Allen GO, Brace CL, Davenport MS, Abel EJ, Wells SA.
Abdom Radiol (NY). 2022 Mar 12. doi: 10.1007/s00261-022-03481-w. Online ahead of print.
PMID: 35278110

Bisphenol-A analogs induce lower urinary tract dysfunction in male mice.
Nguyen JL, Ricke EA, Liu TT, Gerona R, MacGillivray L, Wang Z, Timms BG, Bjorling DE, Vom Saal FS, Ricke WA.
Biochem Pharmacol. 2022 Mar;197:114889. doi: 10.1016/j.bcp.2021.114889. Epub 2022 Jan 1.
PMID: 34979091

Association of Analgesic Block With the Incidence of Complications Following Hypospadias Surgery; A Meta-Analysis.
Adler AC, Bhatia VP, Chandrakantan A, Nathanson BH, Ouellette L, Austin PF.
Urology. 2022 Mar 12:S0090-4295(22)00209-6. doi: 10.1016/j.urology.2022.03.002. Online ahead of print.
PMID: 35292293 Review.

Natural history of simple renal cysts: longitudinal CT-based evaluation.
Wentland AL, Nystrom J, Lubner MG, Mao L, Abel EJ, Pickhardt PJ.
Abdom Radiol (NY). 2022 Mar;47(3):1124-1132. doi: 10.1007/s00261-022-03421-8. Epub 2022 Jan 26.
PMID: 35080631

Disposable Ureteroscopes in Urology: Current State and Future Prospects.
Knoedler MA, Best SL.
Urol Clin North Am. 2022 Feb;49(1):153-159. doi: 10.1016/j.ucl.2021.07.012. Epub 2021 Oct 22.
PMID: 34776048 Review.

Should we treat asymptomatic concurrent contralateral renal stones? A longitudinal analysis.
Li S, Quarrier S, Serrell EC, Penniston KL, Nakada SY.
Urolithiasis. 2022 Feb;50(1):71-77. doi: 10.1007/s00240-021-01281-3. Epub 2021 Jul 16.
PMID: 34272594

A systematic approach for successful repair of radiated and non-radiated ureteral injuries.
Grimes MD, Schubbe ME, Erickson BA.
Transl Androl Urol. 2022 Jan;11(1):30-38. doi: 10.21037/tau-21-574.
PMID: 35242639 Free PMC article.

Effect of Metabolic Syndrome on Anatomy and Function of the Lower Urinary Tract Assessed on MRI.
Tannenbaum AP, Grimes MD, Brace CL, Johnson CJ, Koebe SD, Anzia LE, Mao L, Ricke WA, Hernando D, Roldan-Alzate A, Wells SA.
Urology. 2022 Jan;159:176-181. doi: 10.1016/j.urology.2021.09.006. Epub 2021 Sep 24.
PMID: 34571092

MetaNetwork Enhances Biological Insights from Quantitative Proteomics Differences by Combining Clustering and Enrichment Analyses.
Carr AV, Frey BL, Scalf M, Cesnik AJ, Rolfs Z, Pike KA, Yang B, Keller MP, Jarrard DF, Shortreed MR, Smith LM.
J Proteome Res. 2022 Jan 24. doi: 10.1021/acs.jproteome.1c00756. Online ahead of print.
PMID: 35073098

Epigenetic field alterations in non-tumor prostate tissues detect prostate cancer in urine.
Khemees TA, Yang B, Schultz A, Allen GO, Gawdzik J, Nihal A, Richards KA, Abel EJ, Jarrard DF.
Am J Clin Exp Urol. 2021 Dec 15;9(6):479-488. eCollection 2021.
PMID: 34993267 Free PMC article.

Validation of the Japanese Version of The Wisconsin Stone Quality of Life Questionnaire: Results from SMART Study Group.
Okada T, Hamamoto S, Taguchi K, Okada S, Inoue T, Fukuta H, Chew BH, Penniston K, Okada A, Yasui T.
J Endourol. 2021 Dec;35(12):1852-1856. doi: 10.1089/end.2021.0292.
PMID: 34162226

Serious and Fatal Complications after Neonatal Circumcision.
Schröder A, Farhat WA, Chiasson D, Wilson GJ, Koyle MA.
Eur Urol Focus. 2021 Dec 29:S2405-4569(21)00316-3. doi: 10.1016/j.euf.2021.12.005. Online ahead of print.
PMID: 34973956

Modeling Performance of Open Surgical Cases.
Azari DP, Frasier LL, Miller BL, Pavuluri Quamme SR, Le BV, Greenberg CC, Radwin RG.
Simul Healthc. 2021 Dec 1;16(6):e188-e193. doi: 10.1097/SIH.0000000000000544.
PMID: 34860738

Osteopontin Deficiency Ameliorates Prostatic Fibrosis and Inflammation.
Popovics P, Jain A, Skalitzky KO, Schroeder E, Ruetten H, Cadena M, Uchtmann KS, Vezina CM, Ricke WA.
Int J Mol Sci. 2021 Nov 18;22(22):12461. doi: 10.3390/ijms222212461.
PMID: 34830342

Assessment of Frailty and Association With Progression of Benign Prostatic Hyperplasia Symptoms and Serious Adverse Events Among Men Using Drug Therapy.
Bauer SR, Walter LC, Ensrud KE, Suskind AM, Newman JC, Ricke WA, Liu TT, McVary KT, Covinsky K.
JAMA Netw Open. 2021 Nov 1;4(11):e2134427. doi: 10.1001/jamanetworkopen.2021.34427.
PMID: 34817584

The utility of native ureter in the management of ureteral complications in children after renal transplantation.
Serrell EC, Su R, O’Kelly F, Semanik M, Farhat WA.
Pediatr Transplant. 2021 Nov;25(7):e14051. doi: 10.1111/petr.14051. Epub 2021 May 30.
PMID: 34056809

Evolution of risk stratification systems is critical for improving patient selection for cytoreductive nephrectomy.
Esdaille AR, Abel EJ.
Cancer. 2021 Nov 1;127(21):3920-3923. doi: 10.1002/cncr.33788. Epub 2021 Jul 19.
PMID: 34286855

Gender-related differences in the risk factors for repeat stone surgery.
Iremashvili V, Li S, Dresner SL, Best SL, Hedican SP, Nakada SY.
Urolithiasis. 2021 Oct;49(5):471-476. doi: 10.1007/s00240-021-01255-5. Epub 2021 Feb 11.
PMID: 33575928

Clinical Impact of the Institution of Moses Technology on Efficiency During Retrograde Ureteroscopy for Stone Disease: Single-Center Experience.
Knoedler MA, Li S, Best SL, Hedican SP, Penniston KL, Nakada SY.
J Endourol. 2021 Oct 29. doi: 10.1089/end.2021.0251. Online ahead of print.
PMID: 34235963

Disposable Ureteroscopes in Urology: Current State and Future Prospects.
Knoedler MA, Best SL. Urol Clin North Am. 2022 Feb;49(1):153-159. doi: 10.1016/j.ucl.2021.07.012. Epub 2021 Oct 22.
PMID: 34776048 Review.

Initial Findings from a High Genetic Risk Prostate Cancer Clinic.
Sessine MS, Das S, Park B, Salami SS, Kaffenberger SD, Kasputis A, Solorzano M, Luke M, Vince RA, Kaye DR, Borza T, Stoffel EM, Cobain E, Merajver SD, Jacobs MF, Milliron KJ, Caba L, van Neste L, Mondul AM, Morgan TM.
Urology. 2021 Oct;156:96-103. doi: 10.1016/j.urology.2021.05.078. Epub 2021 Jul 17.
PMID: 34280438

Flexible Ureteroscopy as the New Standard for the Management of Renal Transplant Urolithiasis <15 mm: A Single-Center Experience.
Gerber RC, Best SL, Hedican SP, Nakada SY.J Endourol. 2021 Oct;35(10):1443-1447. doi: 10.1089/end.2020.0473. Epub 2021 Apr 26.
PMID: 33691495

Combined mpMRI/US fusion targeted and concurrent standard biopsies in the detection of prostate cancer: a retrospective study.
Hubbard S, Wells SA, Olson K, Jarrard DF, Huang W. Am J Transl Res. 2021 Oct 15;13(10):12107-12113. eCollection 2021.
PMID: 34786148 Free PMC article.

Combining Stereotactic Body Radiotherapy and Microwave Ablation Appears Safe and Feasible for Renal Cell Carcinoma in an Early Series.
Blitzer GC, Wojcieszynski A, Abel EJ, Best S, Lee FT Jr, Hinshaw JL, Wells S, Ziemlewicz TJ, Lubner MG, Alexander M, Yadav P, Bayouth JE, Floberg J, Cooley G, Harari PM, Bassetti MF.
Clin Genitourin Cancer. 2021 Oct;19(5):e313-e318. doi: 10.1016/j.clgc.2021.04.010. Epub 2021 Apr 20.
PMID: 34024743

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